A World Leader

The Campbell Family Institute at The Princess Margaret is a world leader in basic science employing 228 researchers, 425 trainees, and 622 research staff. Since 2008, our investigators have obtained over $200 million in external funding, produced over 1,000 peer-reviewed publications, given invited presentations at over 800 conferences worldwide, won numerous awards, and filed several patents based on their research.

Because we work alongside the clinicians at Canada’s largest cancer hospital, we also excel at translational science where new discoveries are quickly ‘translated’ into effective therapies that can help patients. This depth of expertise has resulted in a clinical research powerhouse that has:

  • Over 30 percent of new patients enrolled in clinical trials
  • 350 on-going clinical trials, involving over 7,000 patients
  • A drug development program that is the only non-U.S. facility to receive both a Phase I grant and a Phase II contract from the U.S. National Cancer Institute

Basic Science Research

  • Cancer and normal stem cells
  • Signal transduction
  • Cancer genomics/proteomics
  • Tumour metabolism (including hypoxia)
  • Immunotherapy
  • Molecular imaging/GTx
  • DNA damage/repair

Translational Science Research


  • Breast density linked to increased breast cancer risk
  • Paradigm-changing studies in lung cancer treatment
  • Development and implementation of image-guided targeted XRT